Long-term heavy use of alcohol in adolescence alters cortical excitability and functional connectivity in the brain, according to a new study from the University of Eastern Finland and Kuopio University Hospital. These alterations were observed in physically and mentally healthy but heavy-drinking adolescents, who nevertheless did not fulfil the diagnostic criteria for a substance abuse disorder. The findings were published in Addiction Biology.
A new Université de Montréal study in the British Medical Journal reveals that antidepressants prescribed to pregnant women could increase the chance of having a baby with birth defects.
The risk – 6 to 10 %, versus 3 to 5 % in women who do not take the drugs – is high enough to merit caution in their use, especially since, in most cases, they are only marginally effective, the study says.
The use of benzodiazepines and benzodiazepine-like drugs was associated with a 20 per cent increased risk of stroke among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland. Benzodiazepines were associated with a similar risk of stroke as benzodiazepine-like drugs.
Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland. The increased risk was highest at the beginning of antidepressant use and remained elevated even 4 years later. The findings were published in the International Journal of Geriatric Psychiatry.
Depression poses a risk for cardiovascular diseases in men that is just as great as that posed by high cholesterol levels and obesity. This is according to a report recently published in the 'Atherosclerosis' journal by researchers from the Helmholtz Zentrum München, together with colleagues from the Technical University of Munich (TUM) and the German Center for Cardiovascular Disease (DZHK).
Alcohol use disorders (AUDs) develop with time and in stages. Following the initiation of drinking, some people progress to problem drinking, and then develop a “cluster” of specific problems to comprise an AUD. However, not all stages of AUD development have been studied equally. This report examines high-risk families to understand underlying influences across multiple stages of AUD development.