The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance, report EMBL researchers and collaborators in Nature on July 4.
Doctors are beginning to prescribe antibiotic treatments from the 1950s for benign infections to fight antibiotic resistance and preserve the effectiveness of newer antibiotics. But these “old” antibiotics were not tested in the same way as their modern counterparts before being put on the market, particularly in terms of their treatment effectiveness and side effects.
About a decade ago, evolutionary psychologists suggested that humans have evolved a first line of defense against disease: a behavioural immune system (BIS). This system is thought to be unconsciously activated, to varying degrees, when an individual perceives, rightly or wrongly, that there is a threat of disease.
In a new Respirology study, having measles—a highly contagious respiratory infection—during early childhood was linked with an increased risk of developing chronic obstructive pulmonary disease in middle age, but only in adults with asthma and a considerable history of smoking.
A new study indicates that the drug fosfomycin may be effective for treating multidrug-resistant bacterial infections. In most European countries, the oral formulation is only approved as a 3 gram single dose for the treatment of uncomplicated cystitis; however the Pharmacology Research & Perspectives study found that a dosing regimen of 6–12 grams per day divided in 3 doses is required for the treatment of systemic multi-drug-resistant bacterial infections.
Novel five-year study highlights importance of behaviors such as coffee drinking and not smoking on health and survival of HIV-infected patients, report investigators in the Journal of Hepatology