This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Negative Social Media Behaviors May Be ... Certain social media factors were linked with major depressive ... (13 Jan 2019)
Couples Intervention May Help Partners of ... A new Diabetic Medicine study reveals that couples interventions ... (13 Jan 2019)
Could a less sedentary lifestyle help to ... The effects on osteoporosis of prolonged periods of sitting – ... (13 Jan 2019)
Treat vitamin D deficiency to prevent deadly ... Vitamin D supplements have been found to reduce the risk of ... (13 Jan 2019)
Even moderate alcohol consumption is a risk ... A new study published in HeartRhythm reports that regular ... (13 Jan 2019)
Tuesday, 10 April 2018 18:18

Resistance training enhances recycling capacity in muscles Featured

Rate this item
(0 votes)

A new study at the University of Jyväskylä, Finland reports that autophagosome content is increased by resistance training in previously untrained young men, but this response may be blunted by aging.

Autophagy is a major catabolic route in cells responsible for the clearance of proteins and organelles. Pathological levels of autophagy are associated with muscle wasting, but physiological levels are important for cellular recycling.

In the present study, indicators of autophagy and unfolded protein response (UPR), which is another system for maintaining cellular homeostasis, were investigated from the muscle biopsies after a single bout of resistance exercise and after 21 weeks of resistance training in previously untrained young and older men.

“Aging may thus blunt some of the positive effects of resistance training induced improvement in muscle quality,” says PhD student Jaakko Hentilä and Academy of Finland Research Fellow Juha Hulmi.

However, the researchers reported that UPR that is induced by the accumulation of misfolded proteins in endoplasmic reticulum (ER) was activated by a bout of unaccustomed resistance exercise regardless of age. Skeletal muscle appears to adapt to resistance exercise similarly in young and older people in many ways.

The study was conducted in the Faculty of Sport and Health Sciences at the University of Jyväskylä in collaboration with researchers in Oslo.

The results are published in the journal Acta Physiologica. The study was funded by Finnish Cultural Foundation, Academy of Finland and the Finnish Ministry of Education.

 


Source: University of Jyväskylä
Full bibliographic information

Hulmi. Autophagy is induced by resistance exercise in young men but unfolded protein response is induced regardless of age. Acta Physiologica: 

Read 815 times Last modified on Thursday, 12 April 2018 17:50

Latest news

Highlights

Join

Connect with other Medical Professionals on fb in a closed facebook group

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…