This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Synapses of the reward system at stake in ... Autism spectrum disorders are a heterogeneous group of ... (07 Aug 2018)
  A diverse diet may not be the healthiest ... Encouraging people to eat a wide variety of foods to ensure they ... (07 Aug 2018)
Older adults who get physical can lower ... Adults in their early 60s, who spend less time sitting and more ... (07 Aug 2018)
People who sleep for more than eight hours ... A large study led by Keele University has found that sleeping ... (07 Aug 2018)
Learning while sleeping? Our learning ... A group of researchers found that our learning capabilities are ... (07 Aug 2018)
Thursday, 17 May 2018 07:03

Review shows lack of evidence supporting use of antidepressants for insomnia Featured

Rate this item
(0 votes)

A rigorous review of research, led by the University of Southampton, has found there is not enough evidence to support the current clinical practice of prescribing antidepressants for insomnia.


The review, published in the Cochrane Systematic Reviews Library, re-examined 23 previous studies involving a total of 2,806 patients with insomnia.The researchers found that, overall, evidence supporting the use of antidepressants for people with sleep problems is of low quality – partly due to the small number of people in individual studies and partly due to how the studies were undertaken and reported.

Some low quality evidence was identified supporting short term (weeks, rather than months) use of some antidepressants, but no evidence was found for amitriptyline, which is commonly used in clinical practice. There was also no evidence to support long-term antidepressant use for insomnia.

Lead researcher, Associate Professor Hazel Everitt, says: “High quality trials of antidepressants for insomnia are needed to provide better evidence in this area to inform clinical practice. Additionally, health professionals and patients should be made aware of the current lack of evidence for antidepressant medications commonly used for insomnia management.”

Insomnia causes unsatisfactory sleep – both difficulty getting to sleep and staying asleep. It is a common problem, with one in five people reporting sleep problems each year. It can significantly impair quality of life, leading to physical or mental health problems and is associated with anxiety, depression and drug and alcohol abuse.

Management of the condition depends on its duration and nature. It may involve treating coexisting medical problems, providing advice on sleep habits and lifestyle, or using medicines and psychological therapies. Hypnotics are most commonly used to treat insomnia and are known to help, but can have problems, such as tolerance and dependence. The use of antidepressant drugs to help with insomnia is widespread, but none are licensed for the condition and, as this study has shown, their effectiveness is unclear.

The review Antidepressants for insomnia in adults, is published in the Cochrane Database of Systematic Reviews.

The review included past randomised controlled trials of adults with an insomnia diagnosis published in a selection of electronically available databases up to 2015.1


Source: University of Southampton
Full bibliographic information
"Antidepressants for insomnia in adults" The Cochrane Library

Read 217 times Last modified on Tuesday, 22 May 2018 17:49

TheSynapse Videos

0
0
0
0
0
0

Latest news

Highlights

  • WASP Course in Bahrain

    WASP Course, led by Prof Victor Grech and Prof Charles Savona Ventura, has recently organised a course in Bahrain. Co-hosted with Arabian Gulf University, the course, on how to write a scientific paper, focused on quantitative analysis methods and was targeted for medical doctors and allied health professionals.

    Written on April 24, 2018 Read more...
  • Interactive Discussion on Valsartan

     

     

    The Malta Medicines Authority in collaboration with the Superintendence
    of Public Health and the Department of Pharmacy University of Malta
    would like to cordially invite you to an interactive scientific discussion:

     

     


    THE VALSARTAN SAGA


    SCIENCE | MYTHS | REALITIES

     


    led by Professor Anthony Serracino Inglott

     


    Date: Wednesday 25 July 2018

     


    Time: 20:00
    Venue: Conference Room, Life Sciences Park, San Ġwann

     


    Refreshments will be served


    RSVP: info.medicinesauthority@gov.mt | 23439202

    Written on July 21, 2018

Join

Connect with other Medical Professionals on fb in a closed facebook group

captcha  

Login

Template Settings

Theme Colors

Cyan Red Green Oranges Teal

Layout

Wide Boxed Framed Rounded
Patterns for Layour: Boxed, Framed, Rounded
Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…