This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Adult-onset IBD linked to higher mortality While the onset of inflammatory bowel disease (ulcerative ... (17 May 2019)
Children who walk to school less likely to ... Children who regularly walk or cycle to school are less likely ... (20 May 2019)
Women with sleep apnoea are more likely to ... A study of more than 19,000 people has found that women with ... (20 May 2019)
Passion trumps love for sex in relationships When women distinguish between sex and the relational and ... (17 May 2019)
Inflammatory Bowel Disease During Childhood ... A new study revealed an increased risk of cancer and early death ... (13 May 2019)
Thursday, 17 May 2018 07:03

Review shows lack of evidence supporting use of antidepressants for insomnia Featured

Rate this item
(0 votes)

A rigorous review of research, led by the University of Southampton, has found there is not enough evidence to support the current clinical practice of prescribing antidepressants for insomnia.


The review, published in the Cochrane Systematic Reviews Library, re-examined 23 previous studies involving a total of 2,806 patients with insomnia.The researchers found that, overall, evidence supporting the use of antidepressants for people with sleep problems is of low quality – partly due to the small number of people in individual studies and partly due to how the studies were undertaken and reported.

Some low quality evidence was identified supporting short term (weeks, rather than months) use of some antidepressants, but no evidence was found for amitriptyline, which is commonly used in clinical practice. There was also no evidence to support long-term antidepressant use for insomnia.

Lead researcher, Associate Professor Hazel Everitt, says: “High quality trials of antidepressants for insomnia are needed to provide better evidence in this area to inform clinical practice. Additionally, health professionals and patients should be made aware of the current lack of evidence for antidepressant medications commonly used for insomnia management.”

Insomnia causes unsatisfactory sleep – both difficulty getting to sleep and staying asleep. It is a common problem, with one in five people reporting sleep problems each year. It can significantly impair quality of life, leading to physical or mental health problems and is associated with anxiety, depression and drug and alcohol abuse.

Management of the condition depends on its duration and nature. It may involve treating coexisting medical problems, providing advice on sleep habits and lifestyle, or using medicines and psychological therapies. Hypnotics are most commonly used to treat insomnia and are known to help, but can have problems, such as tolerance and dependence. The use of antidepressant drugs to help with insomnia is widespread, but none are licensed for the condition and, as this study has shown, their effectiveness is unclear.

The review Antidepressants for insomnia in adults, is published in the Cochrane Database of Systematic Reviews.

The review included past randomised controlled trials of adults with an insomnia diagnosis published in a selection of electronically available databases up to 2015.1


Source: University of Southampton
Full bibliographic information
"Antidepressants for insomnia in adults" The Cochrane Library

Read 823 times Last modified on Tuesday, 22 May 2018 17:49

Latest news

Highlights

Join

Connect with other Medical Professionals on fb in a closed facebook group

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…