This website is intended for Medical Professionals only. By using this site you confirm that you are a healthcare professional.

News
Compound Derived from Marijuana May Benefit ... In recent years, cannabinoids—the active chemicals ... (20 Nov 2018)
CLINICS AVAILABLE AT RATIONAL PHARMACY CLINICS AVAILABLE  AT RATIONAL PHARMACY , VALLEY ROAD,  B'KARA ... (19 Nov 2018)
Friday, 06 July 2018 16:19

Extended Tamoxifen Therapy May Increase Risk of Endometrial Cancer Featured

Rate this item
(0 votes)

There is clear evidence that extended adjuvant tamoxifen therapy for 10 years reduces local recurrence and improves breast cancer-free survival in women with oestrogen receptor–positive breast cancer.

An analysis of large randomized controlled trials, however, reveals that extended use is linked with a two-fold increased risk of developing endometrial (womb) cancer, when compared with standard 5 years of tamoxifen.

While more research is needed, the BJS(British Journal of Surgery) findings suggest that screening for endometrial cancer may be warranted in patients who receive extended tamoxifen therapy.

"There is a paucity of clear evidence on how we should best manage endometrial cancer risk in extended tamoxifen therapy. This is a research area that requires immediate focus with expansion of extended tamoxifen therapy regimes," said lead author Dr.Christina Fleming, of St. Vincent’s Hospital Group, in Dublin, Ireland.


Source: Wiley
Full bibliographic information

Meta-analysis of the cumulative risk of endometrial malignancy and systematic review of endometrial surveillance in extended tamoxifen therapy, British Journal of Surgery.

 

Read 346 times Last modified on Monday, 09 July 2018 10:35

Latest news

Highlights

  • CLINICS AVAILABLE AT RATIONAL PHARMACY

    CLINICS AVAILABLE  AT RATIONAL PHARMACY , VALLEY ROAD,  B'KARA FOR CONSULTANTS .  GENERAL PRACTITIONER REQUIRED MORNINGS AND AFTERNOONS.

    Written on November 19, 2018

Join

Connect with other Medical Professionals on fb in a closed facebook group

captcha  

Login

Top
We use cookies to improve our website. By continuing to use this website, you are giving consent to cookies being used. More details…