The British Journal of Clinical Pharmacology analysis included 49 case reports and two observational studies with 15 cases of adverse drug reactions. The majority of patients were diagnosed with cardiovascular diseases, cancer, and kidney transplants and were receiving mostly warfarin, alkylating agents, and cyclosporine, respectively.
Investigators noted that patients taking warfarin and/or statins for the treatment of cardiovascular complications reported significant interactions after taking herbal products including sage, flaxseed, St. John’s wort, cranberry, goji juice, green tea, and chamomilla.
Full bibliographic information:
Critical Evaluation of Causality Assessment of Herb-Drug Interactions in Patients. British Journal of Clinical Pharmacology.